MITUS Lab MIcroengineering Therapeutic UltraSound

Publications

Highlighted

A Single-Inductor-Based High-Voltage Transmit Beamformer for Wearable Ultrasound Devices Achieving 88 fCV sup 2 sup Power Reduction
A Single-Inductor-Based High-Voltage Transmit Beamformer for Wearable Ultrasound Devices Achieving 88% fCV2 Power Reduction
Peng Guo, Zu-Yao Chang, Michiel A. P. Pertijs, Tiago L. Costa
2025 IEEE International Solid-State Circuits Conference (ISSCC)  ·  16 Feb 2025  ·  doi:10.1109/ISSCC49661.2025.10904513

All

2025

A Programmable-Gain Floating Inverter Low-Noise Amplifier for Ultrasound Imaging Analog Frontends
A Programmable-Gain Floating Inverter Low-Noise Amplifier for Ultrasound Imaging Analog Frontends
Diogo Dias, Tiago Costa, João Goes
2025 IEEE International Symposium on Circuits and Systems (ISCAS)  ·  25 May 2025  ·  doi:10.1109/ISCAS56072.2025.11043193
Piezoelectric ion gated organic electrochemical transistors for efficient vibration sensing and on-site amplification
Piezoelectric ion gated organic electrochemical transistors for efficient vibration sensing and on-site amplification
Linta Sohail, Sofia Drakopoulou, Tiago L. Costa, George D. Spyropoulos
npj Flexible Electronics  ·  08 May 2025  ·  doi:10.1038/s41528-025-00418-3
A Single-Inductor-Based High-Voltage Transmit Beamformer for Wearable Ultrasound Devices Achieving 88 fCV sup 2 sup Power Reduction
A Single-Inductor-Based High-Voltage Transmit Beamformer for Wearable Ultrasound Devices Achieving 88% fCV2 Power Reduction
Peng Guo, Zu-Yao Chang, Michiel A. P. Pertijs, Tiago L. Costa
2025 IEEE International Solid-State Circuits Conference (ISSCC)  ·  16 Feb 2025  ·  doi:10.1109/ISSCC49661.2025.10904513

2024

Anti-reflective Microengineered Substrate for in vitro Ultrasound Neuromodulation
Anti-reflective Microengineered Substrate for in vitro Ultrasound Neuromodulation
Gandhika K. Wardhana, Tiago L. Costa, Massimo Mastrangeli
2024 IEEE Ultrasonics, Ferroelectrics, and Frequency Control Joint Symposium (UFFC-JS)  ·  22 Sep 2024  ·  doi:10.1109/UFFC-JS60046.2024.10793577
2D Phased Array Driving Scheme Optimization for Ultrasound Neuromodulation
2D Phased Array Driving Scheme Optimization for Ultrasound Neuromodulation
Masoumeh Aqamolaei, Tiago L. Costa
2024 IEEE Ultrasonics, Ferroelectrics, and Frequency Control Joint Symposium (UFFC-JS)  ·  22 Sep 2024  ·  doi:10.1109/UFFC-JS60046.2024.10793494
Feasibility Study for a High-Frequency Flexible Ultrasonic Cuff for High-Precision Vagus Nerve Ultrasound Neuromodulation
Feasibility Study for a High-Frequency Flexible Ultrasonic Cuff for High-Precision Vagus Nerve Ultrasound Neuromodulation
Cornelis van Damme, Gandhika K. Wardhana, Andrada Iulia Velea, Vasiliki Giagka, Tiago L. Costa
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control  ·  01 Jul 2024  ·  doi:10.1109/TUFFC.2024.3381923
A PVT-Robust Open-loop Gm-Ratio 16 Gain Residue Amplifier for gt;1 GS s Pipelined ADCs
A PVT-Robust Open-loop Gm-Ratio ×16 Gain Residue Amplifier for >1 GS/s Pipelined ADCs
Diogo Dias, João Goes, Tiago Costa
2024 IEEE International Symposium on Circuits and Systems (ISCAS)  ·  19 May 2024  ·  doi:10.1109/ISCAS58744.2024.10558154
An Acoustically Transparent Electrical Cap for Piezoelectric Ultrasound Transducers on Silicon
An Acoustically Transparent Electrical Cap for Piezoelectric Ultrasound Transducers on Silicon
Gandhika K. Wardhana, Tiago L. Costa, Massimo Mastrangeli
Eurosensors 2023  ·  19 Mar 2024  ·  doi:10.3390/proceedings2024097050
PMUT and CMUT Devices for Biomedical Applications: A Review
PMUT and CMUT Devices for Biomedical Applications: A Review
Elisabetta Moisello, Lara Novaresi, Eshani Sarkar, Piero Malcovati, Tiago L. Costa, Edoardo Bonizzoni
IEEE Access  ·  01 Jan 2024  ·  doi:10.1109/ACCESS.2024.3359906

2023

Multichannel current-mode stimulator with channel-specific regulated power supply
Multichannel current-mode stimulator with channel-specific regulated power supply
Francesc Varkevisser, Tiago L. Costa, Wouter A. Serdijn
2023 IEEE Biomedical Circuits and Systems Conference (BioCAS)  ·  19 Oct 2023  ·  doi:10.1109/BioCAS58349.2023.10388577
An Energy-Efficient High-Voltage Pulser for High-Frequency Ultrasound Medical Applications
An Energy-Efficient High-Voltage Pulser for High-Frequency Ultrasound Medical Applications
Yidi Xiao, Hassan Rivandi, Tiago L. Costa
2023 IEEE Biomedical Circuits and Systems Conference (BioCAS)  ·  19 Oct 2023  ·  doi:10.1109/BioCAS58349.2023.10388859
Hybrid neuroelectronics: towards a solution-centric way of thinking about complex problems in neurostimulation tools
Hybrid neuroelectronics: towards a solution-centric way of thinking about complex problems in neurostimulation tools
Sofia Drakopoulou, Francesc Varkevisser, Linta Sohail, Masoumeh Aqamolaei, Tiago L. Costa, George D. Spyropoulos
Frontiers in Electronics  ·  12 Sep 2023  ·  doi:10.3389/felec.2023.1250655
A 2D Ultrasound Phased-Array Transmitter ASIC for High-Frequency US Stimulation and Powering
A 2D Ultrasound Phased-Array Transmitter ASIC for High-Frequency US Stimulation and Powering
Hassan Rivandi, Tiago L. Costa
IEEE Transactions on Biomedical Circuits and Systems  ·  01 Aug 2023  ·  doi:10.1109/TBCAS.2023.3288891

2022

Pre-Filtering of Stimuli for Improved Energy Efficiency in Electrical Neural Stimulation
Pre-Filtering of Stimuli for Improved Energy Efficiency in Electrical Neural Stimulation
Francesc Varkevisser, Amin Rashidi, Tiago L. Costa, Vasiliki Giagka, Wouter A. Serdijn
2022 IEEE Biomedical Circuits and Systems Conference (BioCAS)  ·  13 Oct 2022  ·  doi:10.1109/BioCAS54905.2022.9948643
A High-Frequency Beamforming Channel for Ultrasound Stimulation and Ultrasonic Powering
A High-Frequency Beamforming Channel for Ultrasound Stimulation and Ultrasonic Powering
Hassan Rivandi, Ishaan Ghosh, Tiago L. Costa
2022 IEEE Biomedical Circuits and Systems Conference (BioCAS)  ·  13 Oct 2022  ·  doi:10.1109/BioCAS54905.2022.9948550
Maximization of Transmitted Acoustic Intensity from Silicon Integrated Piezoelectric Ultrasound Transducers
Maximization of Transmitted Acoustic Intensity from Silicon Integrated Piezoelectric Ultrasound Transducers
Gandhika K. Wardhana, Massimo Mastrangeli, Tiago L. Costa
2022 IEEE International Ultrasonics Symposium (IUS)  ·  10 Oct 2022  ·  doi:10.1109/IUS54386.2022.9957646
Energy efficiency of pulse shaping in electrical stimulation: the interdependence of biophysical effects and circuit design losses
Energy efficiency of pulse shaping in electrical stimulation: the interdependence of biophysical effects and circuit design losses
Francesc Varkevisser, Tiago L Costa, Wouter A Serdijn
Biomedical Physics & Engineering Express  ·  13 Sep 2022  ·  doi:10.1088/2057-1976/ac8c47
Design of a Flexible Transducer Array and Characterisation of Piezoelectric Sensors for Curvature Compensation
Design of a Flexible Transducer Array and Characterisation of Piezoelectric Sensors for Curvature Compensation
Christiaan Boerkamp, Tiago L. Costa, Jovana Jovanova
ASME 2022 Conference on Smart Materials, Adaptive Structures and Intelligent Systems  ·  12 Sep 2022  ·  doi:10.1115/SMASIS2022-90707
Stent with Piezoelectric Transducers for High Spatial Resolution Ultrasound Neuromodulation- a Finite Element Analysis
Stent with Piezoelectric Transducers for High Spatial Resolution Ultrasound Neuromodulation- a Finite Element Analysis
Ignas Dilevicius, Wouter A. Serdijn, Tiago L. Costa
2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)  ·  11 Jul 2022  ·  doi:10.1109/EMBC48229.2022.9871956
A Parasitic Resistance Extraction Tool Leveraged by Image Processing
A Parasitic Resistance Extraction Tool Leveraged by Image Processing
Diogo Dias, Joao Goes, Tiago Costa
2022 IEEE International Symposium on Circuits and Systems (ISCAS)  ·  28 May 2022  ·  doi:10.1109/ISCAS48785.2022.9937879

2021

An Integrated 2D Ultrasound Phased Array Transmitter in CMOS With Pixel Pitch-Matched Beamforming
An Integrated 2D Ultrasound Phased Array Transmitter in CMOS With Pixel Pitch-Matched Beamforming
Tiago Costa, Chen Shi, Kevin Tien, Jeffrey Elloian, Filipe A. Cardoso, Kenneth L. Shepard
IEEE Transactions on Biomedical Circuits and Systems  ·  01 Aug 2021  ·  doi:10.1109/TBCAS.2021.3096722
Application of a sub 0.1-mm sup 3 sup implantable mote for in vivo real-time wireless temperature sensing
Application of a sub–0.1-mm 3 implantable mote for in vivo real-time wireless temperature sensing
Chen Shi, Victoria Andino-Pavlovsky, Stephen A. Lee, Tiago Costa, Jeffrey Elloian, Elisa E. Konofagou, Kenneth L. Shepard
Science Advances  ·  07 May 2021  ·  doi:10.1126/sciadv.abf6312

2020

A 0.065-mm sup 3 sup Monolithically-Integrated Ultrasonic Wireless Sensing Mote for Real-Time Physiological Temperature Monitoring
A 0.065-mm3Monolithically-Integrated Ultrasonic Wireless Sensing Mote for Real-Time Physiological Temperature Monitoring
Chen Shi, Tiago Costa, Jeffrey Elloian, Yihan Zhang, Kenneth L. Shepard
IEEE Transactions on Biomedical Circuits and Systems  ·  01 Jun 2020  ·  doi:10.1109/TBCAS.2020.2971066
Ablation of piezoelectric polyvinylidene fluoride with a 193 nm excimer laser
Ablation of piezoelectric polyvinylidene fluoride with a 193 nm excimer laser
Jeffrey Elloian, Jeffrey Sherman, Tiago Costa, Chen Shi, Kenneth Shepard
Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films  ·  11 Mar 2020  ·  doi:10.1116/1.5142494
Bidirectional Bioelectronic Interfaces: System Design and Circuit Implications
Bidirectional Bioelectronic Interfaces: System Design and Circuit Implications
Yan Liu, Alessandro Urso, Ronaldo Martins da Ponte, Tiago Costa, Virgilio Valente, Vasiliki Giagka, Wouter A. Serdijn, Timothy G. Constandinou, Timothy Denison
IEEE Solid-State Circuits Magazine  ·  01 Jan 2020  ·  doi:10.1109/MSSC.2020.2987506

2019

A CMOS 2D Transmit Beamformer With Integrated PZT Ultrasound Transducers For Neuromodulation
A CMOS 2D Transmit Beamformer With Integrated PZT Ultrasound Transducers For Neuromodulation
Tiago Costa, Chen Shi, Kevin Tien, Kenneth L. Shepard
2019 IEEE Custom Integrated Circuits Conference (CICC)  ·  01 Apr 2019  ·  doi:10.1109/CICC.2019.8780236

2018

Monolithic Integration of Micron-scale Piezoelectric Materials with CMOS for Biomedical Applications
Monolithic Integration of Micron-scale Piezoelectric Materials with CMOS for Biomedical Applications
C. Shi, T. Costa, J. Elloian, K. L. Shepard
2018 IEEE International Electron Devices Meeting (IEDM)  ·  01 Dec 2018  ·  doi:10.1109/IEDM.2018.8614632

2017

A CMOS Front-End With Integrated Magnetoresistive Sensors for Biomolecular Recognition Detection Applications
A CMOS Front-End With Integrated Magnetoresistive Sensors for Biomolecular Recognition Detection Applications
Tiago Costa, Filipe A. Cardoso, Jose Germano, Paulo P. Freitas, Moises S. Piedade
IEEE Transactions on Biomedical Circuits and Systems  ·  01 Oct 2017  ·  doi:10.1109/TBCAS.2017.2743685

2016

Design and optimization of a CMOS front-end for magnetoresistive sensor based biomolecular recognition detection
Design and optimization of a CMOS front-end for magnetoresistive sensor based biomolecular recognition detection
Tiago Costa, Jose Germano, Moises S. Piedade, Filipe A. Cardoso, Paulo P. Freitas
2016 IEEE International Symposium on Circuits and Systems (ISCAS)  ·  01 May 2016  ·  doi:10.1109/ISCAS.2016.7539189
Semi-Quantitative Method for Streptococci Magnetic Detection in Raw Milk
Semi-Quantitative Method for Streptococci Magnetic Detection in Raw Milk
Carla Duarte, Tiago Costa, Carla Carneiro, Rita Soares, Andrei Jitariu, Susana Cardoso, Moisés Piedade, Ricardo Bexiga, Paulo Freitas
Biosensors  ·  27 Apr 2016  ·  doi:10.3390/bios6020019

2015

Live demonstration: A CMOS ASIC for precise reading of a Magnetoresistive sensor array for NDT
Live demonstration: A CMOS ASIC for precise reading of a Magnetoresistive sensor array for NDT
Diogo M. Caetano, Moises Piedade, Joao Graca, Jorge Fernandes, Luis Rosado, Tiago Costa
2015 IEEE International Symposium on Circuits and Systems (ISCAS)  ·  01 May 2015  ·  doi:10.1109/ISCAS.2015.7169039

2014

A Neuronal Signal Detector for Biologically Generated Magnetic Fields
A Neuronal Signal Detector for Biologically Generated Magnetic Fields
Tiago Costa, Moises S. Piedade, Jose Germano, Jose Amaral, Paulo P. Freitas
IEEE Transactions on Instrumentation and Measurement  ·  01 May 2014  ·  doi:10.1109/TIM.2013.2296417

2013

Integration of TMR Sensors in Silicon Microneedles for Magnetic Measurements of Neurons
Integration of TMR Sensors in Silicon Microneedles for Magnetic Measurements of Neurons
Jose Amaral, Vitor Pinto, Tiago Costa, Joao Gaspar, Ricardo Ferreira, Elvira Paz, Susana Cardoso, Paulo P. Freitas
IEEE Transactions on Magnetics  ·  01 Jul 2013  ·  doi:10.1109/TMAG.2013.2239274
CMOS instrumentation system for matrix-based magnetoresistive biosensors
CMOS instrumentation system for matrix-based magnetoresistive biosensors
Tiago Costa, Moises S. Piedade, Filipe A. Cardoso, Paulo P. Freitas
2013 IEEE International Instrumentation and Measurement Technology Conference (I2MTC)  ·  01 May 2013  ·  doi:10.1109/I2MTC.2013.6555626
An instrumentation system based on magnetoresistive sensors for neuronal signal detection
An instrumentation system based on magnetoresistive sensors for neuronal signal detection
Tiago Costa, Moises S. Piedade, Jose Germano, Jose Amaral, Paulo P. Freitas
2013 IEEE International Instrumentation and Measurement Technology Conference (I2MTC)  ·  01 May 2013  ·  doi:10.1109/I2MTC.2013.6555579
Measuring brain activity with magnetoresistive sensors integrated in micromachined probe needles
Measuring brain activity with magnetoresistive sensors integrated in micromachined probe needles
José Amaral, João Gaspar, Vitor Pinto, Tiago Costa, Nuno Sousa, Susana Cardoso, Paulo Freitas
Applied Physics A  ·  26 Feb 2013  ·  doi:10.1007/s00339-013-7621-7

2012

Integration of Magnetoresistive Biochips on a CMOS Circuit
Integration of Magnetoresistive Biochips on a CMOS Circuit
F. A. Cardoso, T. Costa, J. Germano, S. Cardoso, J. Borme, J. Gaspar, J. R. Fernandes, M. S. Piedade, P. P. Freitas
IEEE Transactions on Magnetics  ·  01 Nov 2012  ·  doi:10.1109/TMAG.2012.2198449
An ultra-low noise current source for magnetoresistive biosensors biasing
An ultra-low noise current source for magnetoresistive biosensors biasing
T. Costa, M. S. Piedade, M. Santos
2012 IEEE Biomedical Circuits and Systems Conference (BioCAS)  ·  01 Nov 2012  ·  doi:10.1109/BioCAS.2012.6418507

2011

A CMOS circuit for precise reading of matrix addressed magnetoresistive biosensors
A CMOS circuit for precise reading of matrix addressed magnetoresistive biosensors
Tiago Costa, Moises S. Piedade, Jorge R. Fernandes
2011 IEEE Biomedical Circuits and Systems Conference (BioCAS)  ·  01 Nov 2011  ·  doi:10.1109/BioCAS.2011.6107809